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<meta charset="utf-8" /><b id="docs-internal-guid-2f10d7f9-7fff-88cf-e23d-d9f68ca79923">TfR1 농도를 향상시키는 것 외에도, 외인성 철 이온의 전달은 펜톤 반응을 통해 ROS 생성을 촉매하여 LPO 축적을 촉진하는 능력도 가지고 있습니다. 이 과정은 세포의 항산화 방어 기제를 직접적으로 압도하고 궁극적으로 페로프토시스를 유발합니다. Zhou 등은 갈산-Fe와 파클리탁셀(PTX)로 구성된 초음파 반응성 나노입자(FeP NPs)를 사용하여 종양 세포에서 철 축적을 활용해 페로프토시스를 유도하는 치료 전략을 보고했습니다.28 기계론적 으로 , FeP NPs 내의 철 이온은 펜톤 반응을 촉진하여 높은 수준의 ROS를 생성하고 산화 스트레스를 유발합니다. 또한, 페로프토시스와 PTX의 세포 사멸 효과가 결합되어 미토콘드리아 손상 및 산화 스트레스 연쇄 반응을 일으켜 상당한 종양 세포 사멸을 초래합니다. 이러한 페로프토시스-세포 사멸 시너지 효과는 효율적인 암 치료를 위한 유망한 방향을 제시합니다. 또한, Liu 등은 소라페닙(SRF) 나노복합체를 사용하여 종양 세포에 직접 철을 전달함으로써 페로프토시스를 유도하는 전략을 제시했습니다. 29 세포 내 철 농도가 증가하면 펜톤 반응이 강화되어 페로프토시스가 촉진됩니다.</b><a class="seoquake-nofollow" href="https://esports-green.isweb.co.kr/" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">bj롤배팅</span></a> <a class="seoquake-nofollow" href="https://bjlol.clickn.co.kr/" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span 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