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<br /> <meta charset="utf-8" /> <p dir="ltr"><b id="docs-internal-guid-1a3a3188-7fff-c36b-f720-a6f4be808994">38 , 39 PLGA 는 폴리락트산과 폴리글리콜산의 생분해성 공중합체입니다. 락타이드-글리콜라이드 비율에 따라 분자량, 결정성 및 분해 속도와 같은 생화학적 특성을 제어할 수 있습니다. 우수한 생체 적합성과 접착 특성에도 불구하고 PLGA의 주요 단점은 분해 시 산성 분자를 방출한다는 것입니다. PEG는 수용성 비이온성 고분자입니다. 중합 조건을 조절함으로써 분자량, 결정성, 수용액에서의 점도와 같은 물리화학적 특성을 제어할 수 있다. PEG는 본질적으로 생체 활성이 낮기 때문에 생의학 응용 분야에서는 세포 접착 단백질 및 성장 인자와 같은 생체 활성 분자를 첨가해야 한다. 리린(Reelin)이 풍부하게 함유된 PLGA-PEG 미셀은 신경 줄기 세포의 동적 성장 및 신경 분화를 촉진하고 국소 혈관 신생을 유도하여 광혈전성 뇌졸중 마우스 모델에서 기능 회복을 나타냈다. 40</b></p> <p dir="ltr"><b id="docs-internal-guid-1a3a3188-7fff-c36b-f720-a6f4be808994">지지체 공학의 발전으로 재생 환경을 능동적으로 조절하는 구조물을 제작할 수 있게 되었습니다. 자가 조립 펩타이드(SAP) 기반 하이드로겔은 높은 생체 적합성과 구조적 조절성을 제공하지만 기계적 강도가 부족할 수 있습니다. </b></p> <a href="https://esports-green.isweb.co.kr/" target="_blank" style="font-size:0;line-height:0;text-decoration:none;" rel="nofollow noreferrer noopener" class="seoquake-nofollow"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">bj롤배팅</span></a> <a href="https://bjlol.clickn.co.kr/" target="_blank" style="font-size:0;line-height:0;text-decoration:none;" rel="nofollow noreferrer noopener" class="seoquake-nofollow"> <span 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