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그림 뷰어 그림 1. 생물학적 메커니즘을 활용하여 시너지 효과를 내는 철-암 치료를 위한 나노유도체를 설계하는 개략도 NDDS 매개 다중 분자 경로를 통한 페롭토시스 증진 페롭토시스는 지질의 철 의존성 과산화에 의해 유발되는 세포 사멸의 한 유형입니다. 이 과정은 분자 수준에서 상당한 화학적 복잡성을 나타내므로 표적화할 수 있는 다양한 기회를 제공합니다. 기능성 나노 운반체 역할을 하는 NDDS는 여러 유도 물질을 동시에 전달하여 반응물 투여량 조절, 전자 전달 제어, 반응 조건 조정과 같은 세포 내 분자 반응을 조절할 수 있으며, 이는 페롭토시스의 치료 효과를 크게 향상시킬 수 있습니다( 표 1 ). 전략 나노소재 생물학적 메커니즘 참고. 반응물 투여량 조절 T 10 변형 리포산 소포체(T 10 @cLAV) 트랜스페린을 탈취하여 배송 장 등25 – iRGD 접합 BSA-CoCl₂ 나노 복합체(iCoDMSN) TfR 발현 증진 자오 등26 – DHA가 함유된 철계 MOF(DHA@MIL-101 NRs) TfR 발현 증진 양 등27 – 갈산-Fe 및 BSA 껍질을 갖는 PTX(GA-Fe(III)@BSA@PTX) 외부에서 철 이온을 공급하는 것 왕 등28 <a class="seoquake-nofollow" href="https://blacktv99.clickn.co.kr/" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">블랙티비</span></a> <a class="seoquake-nofollow" href="https://blacktv88.clickn.co.kr/" rel="nofollow noreferrer 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