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뇌에서 GLUT2는 섭식 및 체온 조절뿐만 아니라 교감신경 및 부교감신경 기능에도 관여합니다[ 29–31 ]. 뇌의 시상하부 영역에 존재하는 특수 신경교 세포인 타니세포는 GLUT1과 GLUT2를 모두 발현합니다. 포도당은 GLUT2를 통해 운반되어 글루코키나아제에 의해 포도당 6-인산으로 전환된 후 ATP 수준이 증가하는 것으로 추정됩니다. 타니세포는 2-데옥시글루코스 및 메틸 글루코피라노사이드와 같은 대사되지 않는 포도당 유사체에도 반응하는 것으로 밝혀져 GLUT2를 통한 대사 독립적인 포도당 감지를 시사합니다[ 32 ]. 또한 설치류 연구에서는 타니세포가 미각 수용체인 TAS1R2 및 TAS1R3을 통해 포도당을 감지할 수 있음을 보여줍니다[ 33 ]. 이러한 연구 및 기타 연구[ 34–36 ]에도 불구하고 GLUT2가 수송 능력 외에도 독립적인 포도당 센서로서의 역할을 명시적으로 입증하기 위해서는 보다 직접적이고 명확한 증거가 필요합니다. <a class="seoquake-nofollow" href="https://zzgtv.com" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">짱구스포츠</span></a> <a class="seoquake-nofollow" href="https://totogal.net/" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span 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